Gut Microbiome and Cognitive Wellness
In our earlier discussion , we highlighted the altered abundance of bacteria in the brains of AD patients, pinpointing significant species such as Cutibacterium acnes, Acinetobacter, and Comamonas genera and a potential link between the brain microbiome and AD pathogenesis. A more recent study, published in October , , has contributed compelling evidence of the gut microbiota's involvement in the development of Alzheimer's disease. This study utilized the technique of fecal microbiota transplantation (FMT), transferring gut microbiota from Alzheimer's patients to healthy young rats. The outcomes were profound, as the transplanted microbiota induced memory impairment and a reduction in pattern separation—an essential ability to distinguish between highly similar events or environments. The study's findings emphasize a critical correlation between specific microbial compositions and cognitive performance in Alzheimer's disease. Notably, the decrease in the abundance ...