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Microbes of Autobrewery Syndrome

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Auto-Brewery Syndrome (ABS), also known as gut fermentation syndrome (GFS), is an unusual condition that causes elevated levels of alcohol in the blood and symptoms of alcohol intoxication, even in patients who have had little to no alcohol intake. This can lead to failed breathalyzer tests, neurocognitive disturbances, and social and legal consequences for those affected. Our earlier studies showed that the majority of MEBO and PATM sufferers, representing a subtype of this condition, have at least a mild form of this syndrome ( elevated alcohol in sugar challenge test).  Recent research has shed new light on the gut microbiome's role in ABS, highlighting it as a disorder of dysbiosis and showing the potential for targeted interventions that address the underlying microbial imbalances associated with the condition.  A 58 years old female presented with mild cognitive impairment, behavioral disturbances, and recurrent encephalopathy episodes. The history of hemicolectomy, an od